PCOS Hormone Support

Your PCOS Isn't a Hormone Problem. It's the Inflammation Behind It.

A black seed oil studied on women with PCOS — to calm the inflammation driving your weight, skin, and cycle struggles, and reach what your meds can't.

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4.9 / 5 Stars
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Black Cumin Seed Oil
USDA Organic
Cold-Pressed
Non-GMO
GMP Certified
3rd Party Tested

You've been treating the symptoms. Not what's causing them.

Most solutions work on the surface. Loomi works on the system underneath — the one driving the symptoms in the first place.

Missing periods
Weight gain
Acne
Facial hair
Insulin resistance
Androgen excess
Inflammation

Stop chasing symptoms. Start with the root.

What Birth Control and Metformin Can't Do

Birth control masks your hormones. Metformin partially addresses insulin resistance. Neither one touches the NF-κB inflammatory cascade that's driving the insulin resistance, the androgen overproduction, and every symptom you're still dealing with.

Targets the Inflammatory Cascade at the Source

Your medication manages the output. This calms the NF-κB overactivation driving the insulin resistance that drives the androgen overproduction. The beginning of the chain — not the end.

Clinically Tested on 114 Women With PCOS

In a randomized controlled trial, women taking Nigella sativa showed reduced ovarian volume, lower testosterone, improved hormonal balance, and more regular cycles — comparable to the prescription drug.

Safe Alongside Everything You're Already Taking

Won't interfere with birth control, metformin, spironolactone, or inositol. No hormonal disruption. No GI side effects. Works with your current protocol — not against it.

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★★★★★ (4,771) 8,000+ Happy Customers

PCOS Hormone Support

High TQ Black Seed Oil by Loomi

Calms Root-Cause Inflammation
Clinically Tested
100% Natural
Clinicians' Choice

586 clinicians share this on FrontrowMD without compensation.

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60-Day Money-Back Guarantee
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Benefits

Our high-TQ black seed oil works on the inflammation underneath PCOS — so support shows up where you actually feel it:

  • Supports a more regular cycle
  • Helps calm hormonal breakouts and skin flare-ups
  • Targets the inflammation tied to stubborn weight
  • Supports steadier energy and mood
  • Gentle, natural formula — one simple daily dose
Why Everything Else Fails

Every PCOS fix you've tried does the same thing.

It chases a symptom.

The pill, metformin, spearmint tea, cutting carbs, the endless supplement stack.

Different tools, same approach. But none of them touch the reason the symptoms keep coming back.

Underneath PCOS is chronic, low-grade inflammation. It's what feeds the insulin resistance — and the insulin resistance is what pushes your body to overproduce androgens, the hormones behind the weight, the skin, the hair, and the cycles that won't cooperate.

The pill smooths your cycle and calms your skin while you're on it. The moment you stop, it all comes back — because the inflammation underneath was never addressed.

Metformin works on your blood sugar. Helpful for some — but it's aimed downstream of the real problem, and the bloating and stomach issues send a lot of women looking for something gentler.

Spearmint tea, inositol, the half-finished bottles in your cabinet. Each one targets a single piece. None of them quiet the inflammation feeding all of it.

And cutting carbs harder and harder? You white-knuckle it, the scale barely moves, and you're left feeling like your body is broken — when it's actually doing exactly what an inflamed, insulin-resistant body does.

So the question isn't "which symptom do I treat next?"

The question is: what's feeding all of them at once?

That's the layer high-TQ black seed oil is made to work on.

How It Works

What if you calmed the root — instead of chasing each symptom?

This is where it gets interesting.

There's a reason black seed (Nigella sativa) oil has been used in traditional medicine for over 2,000 years — and why it's suddenly everywhere again.

Its power comes down to one compound: thymoquinone, or TQ.

TQ has been studied for its effect on NF-κB — one of the body's main "inflammation switches." When that switch is stuck on, it drives the chronic, low-grade inflammation that sits underneath PCOS.

And that inflammation is the first domino. It feeds the insulin resistance. The insulin resistance pushes your body to overproduce androgens — the hormones behind the weight, the skin, the hair, and the cycles that won't settle.

Our formula is built around high-TQ oil — concentrated for the active compound and cold-pressed so it stays intact — to support the body at that inflammation layer, instead of masking one symptom at a time.

Because it works on the root layer rather than forcing a single hormone up or down, it supports your whole system gently — without the on-it, off-it whiplash of options that only work while you keep taking them.

Most women notice changes gradually over weeks, not overnight — often steadier energy first, then skin and cycle as the inflammation settles with consistent daily use.

Who It's For

Made for the woman who's done trying everything.

If you're trying to conceive and PCOS is in the way — the irregular or missing cycles, never knowing if or when you ovulate, the negative tests month after month — you're not imagining how hard this is. PCOS is the most common reason for this kind of cycle disruption, and it traces back to the same root: the inflammation and insulin resistance throwing your hormones off balance. Supporting that root is about helping your body find its own rhythm again, which is the foundation a regular cycle is built on.

If you've fought facial or body hair for years — the secret 4 a.m. shave, tweezers stashed in every bag, the small meltdown when you forget a razor — this works on the hormonal driver underneath the hair, not just the surface. It supports the body at the inflammation-and-androgen layer that makes hormonal hair so stubborn in the first place.

If the scale won't move no matter what you do — you eat less than your friends, you do everything "right," and it barely budges. It was never your willpower. An inflamed, insulin-resistant body holds on to weight, and this is made to support that exact layer.

If hormonal acne keeps flaring along your jaw and chin — the deep, cyclical breakouts that no face wash ever touched because they were never really a skin problem. They're downstream of the same root.

If your cycle does whatever it wants — twelve periods in seven months, or none for months — the unpredictability that runs your whole life. Supporting the root helps the body find a steadier rhythm over time.

If you've spent years being dismissed — told it's "just stress," "just lose weight," or all in your head — you're not crazy and you're not alone. This was built for the women that advice failed.

If you're burned out on the pill and metformin — tired of side effects and of fixes that only work while you're on them — this is the gentle, root-layer option a lot of women look for next.

Here's what most women discover: you don't have just one problem. The woman fighting chin hair is also fighting the weight, the breakouts, and the cycle. They all trace back to the same root — the inflammation feeding the whole picture. That's why working on that one layer, consistently, day after day, is what moves everything at once. Give it a full 90 days and treat the cause, not the symptoms one at a time.

Is All Black Seed Oil The Same?

No — and the difference is the entire reason most black seed oil does nothing.

The active compound that matters is thymoquinone (TQ) — and it's fragile. It's sensitive to heat, light, and air. The moment you push the seeds through a hot industrial press, most of the TQ degrades.

That's how the cheap stuff is made: high-heat extraction, because it's faster and squeezes more oil out of every batch. You end up with a bottle that smells right and looks right — but barely has enough active TQ left to do anything.

Ours is cold-pressed from the raw seed and concentrated for high TQ. Cold-pressing costs more and yields less oil per batch — but it protects the active compound at full strength, which is the whole point.

That's why our oil works and the bargain-bin versions don't. It was never about the plant. It's about what's actually left in the bottle after extraction.

Cold-pressed. High-TQ. Third-party tested. Trusted by thousands of women who'd already tried the rest.

Ingredients

One ingredient. Nothing to hide behind.

Active Ingredient Black Seed Oil (Nigella sativa)
Standardized To 2% Thymoquinone (TQ)
Strength 500 mg per capsule
Count 60 capsules

Cold-pressed and standardized to a guaranteed 2% thymoquinone — the active compound that actually matters. No fillers, no proprietary-blend hiding, no padding the label with a dozen "support" ingredients at doses too small to count.

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Real women, real results

Maya, 29★★★★★
Calms Inflammation Balanced Cycle

"Honestly the one supplement I refuse to run out of now."

I'd tried so many things that did nothing for me. This became part of my daily routine straight away and I actually look forward to taking it… Read more

Priya, 34★★★★★
100% Natural Clinically Tested

"Easiest change I've made — and the only one that actually stuck."

I was skeptical about trying yet another oil, but the quality is obvious and a daily dose has been effortless to keep up with… Read more

Jenna, 41★★★★★
Calms Inflammation 100% Natural

"I only wish I'd started taking it sooner."

After reading up on high-TQ black seed oil I decided to give it a real shot. A few weeks in and I'd already told my sister about it… Read more

The Results Speak for Themselves

What Our Customers Are Saying

Women who spent years on birth control and metformin feeling "managed" on paper but still dealing with acne, hair loss, and absent periods are finally seeing real changes.

★★★★★

"I came off birth control 4 months ago and didn't crash. No jawline explosion. No hair falling out. My cycles are landing every 33 days. After 7 years on the pill I was bracing for the worst. This is the only thing I added."

Brittany K.
Verified Buyer
★★★★★

"My free testosterone dropped into normal range for the first time in 5 years. My endocrinologist asked what I changed. I told her. She just stared at the labs. I've been on metformin for 3 years and it never did this."

Alyssa R.
Verified Buyer
★★★★★

"8 weeks in. Jawline acne is almost gone. I stopped the spironolactone a month ago and my skin is BETTER than it was on it. I had 8 supplement bottles on my counter. Now I have 3. This was the missing piece."

Rachel M.
Verified Buyer

Stop Managing the Symptoms.
Start Addressing the Cascade.

Your medications manage the hormonal output. Black cumin seed oil addresses the NF-κB inflammatory cascade driving everything upstream — clinically tested on 114 women with PCOS showing reduced testosterone, improved cycles, and smaller ovarian volume.

100% Pure Oil

Cold-pressed, no fillers, no carrier oils, no dilution

2% TQ Verified

Every batch tested for thymoquinone potency

114-Woman RCT

Randomized controlled trial on PCOS patients — published 2024

Safe With Your Stack

Won't interfere with birth control, metformin, spiro, or inositol

Try It Risk-Free — 90-Day Guarantee

Common Questions

Frequently Asked Questions

Everything PCOS patients want to know before trying high-TQ black cumin seed oil.

Will this interfere with my birth control or metformin?

No. Thymoquinone works on the NF-κB inflammatory cascade. Birth control works on hormonal suppression. Metformin works on insulin sensitivity. They target completely different systems. Safe to take alongside both, as well as spironolactone and inositol.

How long before I notice a difference?

Many customers notice skin changes and reduced oiliness within 2-4 weeks. The clinical trial measured significant improvements in hormonal balance, ovarian volume, and cycle regularity at 16 weeks. We recommend committing to at least 8-12 weeks before testing labs.

Can I take this with inositol?

Yes — and they complement each other. Inositol improves insulin signaling at the cellular level. Thymoquinone suppresses the NF-κB inflammatory cascade upstream of insulin resistance. They work on different parts of the same problem. Many of our customers take both and report better results than either alone.

I'm trying to conceive. Is this safe?

Nigella sativa has been used for centuries and has a strong safety profile. The clinical trial was conducted on adolescents and showed improved hormonal balance and cycle regularity. However, we always recommend consulting your OB-GYN or reproductive endocrinologist before adding any supplement when actively trying to conceive.

Where is your black seed oil sourced from?

Our Nigella sativa is sourced from the regions where it has been traditionally cultivated for centuries — primarily Egypt and Turkey, where the soil and climate produce the highest natural thymoquinone concentrations. The oil is cold-pressed at the source to preserve the active compound, then formulated, encapsulated, and third-party tested in the USA. Every batch is verified to meet our 2% TQ standardization before it ships.

How is this different from the black seed oil at my grocery store?

Most generic black seed oil contains less than 1% thymoquinone — the active compound behind the clinical results. Ours is standardized to 2% TQ, verified by third-party testing. The concentration matters. It's the difference between drinking grape juice and taking the active compound.

What is your return policy?

90-day money-back guarantee. The clinical trial ran for 16 weeks — we give you 90 days so you have time to take it consistently and see how your body responds. If you're not satisfied, contact us for a full refund. No questions asked.

8,000+
Women Trust Our Formula
★★★★★

"I've been on birth control since I was 16, metformin since 22, and inositol for 2 years. Nothing moved my testosterone. 10 weeks on this and my endocrinologist said my labs look like a different person. I'm 28 and I finally feel like my body is working."

Black Cumin Seed Oil

The Only Compound Clinically Tested Head-to-Head Against a PCOS Drug

Nigella sativa has been used for thousands of years across the Middle East, North Africa, and South Asia for hormonal and inflammatory conditions. But tradition alone isn't why we're here.

In 2024, researchers published a randomized controlled trial on 114 adolescents with PCOS. After 16 weeks, the Nigella sativa group showed reduced ovarian volume, lower testosterone, improved LH-to-FSH ratio, reduced hirsutism scores, and more regular menstrual cycles — comparable results to medroxyprogesterone, the standard pharmaceutical treatment.

"Nigella sativa demonstrated comparable efficacy to medroxyprogesterone in improving menstrual regularity, hormonal balance, and ovarian morphology in adolescents with polycystic ovary syndrome."
— Journal of Ovarian Research, 2024

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Your Treatment Plan Has Been Missing This

Cold-pressed Nigella sativa, standardized to 2% thymoquinone, third-party tested for purity and potency. The one compound that addresses the inflammatory cascade your medication can't touch. Delivered to your door with a 90-day money-back guarantee.

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90-Day Money-Back Guarantee — No Questions Asked

Loved By 8,000+ Women On The TTC Journey

See what our PCOS customers are saying about our formula

M
Megan T. - didn't think i'd ever say this
★★★★★Verified Purchase
Reviewed in the United States on May 14, 2026

i have PCOS and went almost a full year without a period at one point. we'd been trying for a baby and i'd honestly given up on my body doing anything on its own. started this in february. march — nothing. april — a period, on its own, no provera, no nothing. then another one 31 days later. i sat on the bathroom floor and just stared at the test strip drawer. three months in a row now my cycle has shown up by itself. for the first time in years i can actually see when i'm ovulating instead of guessing. i'm not promising anyone anything but i finally feel like my body is back in the game.

64 people found this helpful
D
Dani K. - the ovulation strips are finally turning positive
★★★★★Verified Purchase
Reviewed in the United States on April 27, 2026

two years of TTC. every single month i'd pee on an ovulation strip and the line stayed faint. faint. faint. my RE said i probably wasn't ovulating regularly because of the PCOS and that's why nothing was happening. i'd read about the thymoquinone study so i figured what's another bottle. week 6 i got the first clear positive strip i have ever seen in my life. blazing. i texted a photo of it to my best friend at 6 in the morning. nothing is guaranteed and i know that better than anyone, but watching that line finally go dark felt like my body remembered what it's supposed to do.

51 people found this helpful
P
Priya S. - for the girls crying in the fertility clinic parking lot
★★★★★Verified Purchase
Reviewed in the United States on April 9, 2026

if you have PCOS and you're trying to conceive then you already know the specific kind of exhaustion i'm talking about. the appointments. the "just lose weight" from doctors who don't get it. the cycles that never come. i'm not going to oversell this to you because i hate it when people do that. but my cycles went from completely random to roughly 30-32 days within about 10 weeks. my skin calmed down, the dark chin hairs slowed way down — those are real hormonal markers, not in my head. i'm still on this road but i walked into my last appointment with actual data instead of dread for once.

47 people found this helpful
H
Hannah B. - researched it to death first (engineer, sorry)
★★★★★Verified Purchase
Reviewed in the United States on March 22, 2026

i don't buy supplements on vibes. i'm an engineer and i went and read the actual 2024 trial before i spent a single dollar. standardized 2% TQ versus the sub-1% stuff all over amazon — that distinction is real and it actually matters. i have PCOS with anovulatory cycles, the whole picture. i'm 11 weeks in now. my cycle length has stabilized into a window i can finally predict for the first time since high school, which when you're trying to conceive is basically everything. it's doing the thing the data said it might do, which is all i was asking for.

39 people found this helpful
C
Carla M. - my husband asked why i was crying happy tears
★★★★★Verified Purchase
Reviewed in the United States on February 16, 2026

married 4 years, PCOS diagnosis, trying for most of that time. i'd genuinely stopped expecting my period to show up without medication. and then it just did. day 33. then it came again. my husband walked into the bathroom and i was crying and he completely panicked until i explained they were the good kind of tears. i'm not going to pretend a bottle is a miracle and i won't insult you like that. but having a cycle i can track again, feeling like ovulation is even on the table after years of nothing — that's hope i did not have last spring, and right now that's worth everything to me.

33 people found this helpful