Shop Loomi black seed oil for PCOS
Loomi black seed oil for PCOS
  • ★★★★★

    I can sit through a movie again

    Two years of planning my entire life around bathroom access. Elmiron did nothing. The IC diet helped a little but I was still going 18 times a day. Month two on this and I'm down to maybe 10. I cried in a Target because I walked the whole store without stopping.

    -Brianna

    Verified Customer

  • ★★★★★

    The burning finally eased

    Every urologist treated me like I had a UTI that just wouldn't quit. Antibiotics over and over. Culture always came back clean. Nobody could explain why it still burned. Six weeks in and the pressure is the lowest it's been in over a year. Not gone. But manageable for the first time.

    -Tamara

    Verified Customer

  • ★★★★★

    Wish I found this sooner

    I'd already quit coffee, tomatoes, citrus, wine, spicy food. Basically everything I loved. Tried marshmallow root, aloe vera, D-mannose. The inflammation angle was the first thing that actually explained why my bladder lining wasn't healing. I'm sleeping through the night now. That alone is worth it.

    -Lauren

    Verified Customer

  • ★★★★★

    My flares actually calmed down

    Used to flare every single week no matter what I did. Hydroxyzine took the edge off but I was a zombie all day. Around week five the flares started spacing out. I've had two in the last six weeks instead of six. Still careful with my diet but I have breathing room now.

    -Jessica

    Verified Customer

  • ★★★★★

    Not overnight but real

    Month one I almost gave up. Nothing changed. Somewhere around week six the urgency started dropping. I'm not "cured" and I don't think that word even applies to IC. But I drove three hours last weekend without stopping once and that hasn't happened in two years.

    -Megan

    Verified Customer

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★★★★★ (4,771) 8,000+ Happy Customers

IC Root Cause Support

High TQ Black Seed Oil by Loomi

Calms Bladder Inflammation
Research-Backed Mechanism
100% Natural
Clinicians' Choice

586 clinicians share this on FrontrowMD without compensation.

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100% Vegan · Doctor Approved · FDA Registered Facility
Why Everything Else Fails

Most IC treatments chase symptoms one at a time. Antihistamines dull the urgency. Elmiron coats the lining. Dietary restrictions remove triggers. But none of them touch the reason your bladder lining broke down in the first place: chronic inflammation. High-TQ black seed oil is studied for its effect on that upstream cause instead.

How It Works

Your bladder has a protective lining called the GAG layer. When that lining breaks down, irritants in your urine reach the bladder wall and trigger pain, urgency, and frequency. Inflammation is what degrades that lining and keeps it from rebuilding.

Black seed oil contains a compound called TQ that's been studied for its effect on that inflammatory process. Our oil is cold-pressed to keep the TQ intact. Most women notice small shifts within a few weeks, with deeper changes building over time.

How Long Will It Take To See Results?

Most women notice sleep improvements and reduced nighttime urgency within the first 2-3 weeks. Flare frequency and daytime urgency typically start improving around weeks 5-7.

Give it a full 90 days for the best picture of what it can do — that's why we offer a 90-day money-back guarantee.

Can I Take It With Other Supplements Or Medications?

Yes. Loomi is designed to work alongside your current routine — not replace it. Women take it with Elmiron, hydroxyzine, amitriptyline, D-mannose, marshmallow root, aloe vera, and more.

One ingredient, no drug interactions at normal doses. As always, check with your doctor before adding anything new.

Is All Black Seed Oil The Same?

No. Most black seed oil is made with high heat, which destroys the good part called TQ. Ours is cold-pressed, so the TQ stays strong. That's why ours works and cheap ones don't.

Ingredients

One ingredient. Nothing to hide behind.

Active Ingredient Black Seed Oil (Nigella sativa)
Standardized To 2% Thymoquinone (TQ)
Strength 500 mg per capsule
Count 60 capsules

Cold-pressed and standardized to a guaranteed 2% thymoquinone — the active compound that actually matters. No fillers, no proprietary-blend hiding, no padding the label with a dozen "support" ingredients at doses too small to count.

Real women, real results

Tamara, 38★★★★★
Calms Inflammation Better Sleep

"I slept through the night for the first time in months"

Was getting up four or five times a night. Around week three it dropped to twice. By week seven, most nights I sleep straight through. That alone changed everything.

Angela, 41★★★★★
100% Natural Works With Meds

"my flares finally started spacing out"

Still on hydroxyzine and the IC diet. Added this about ten weeks ago. Used to flare every single week. Last month I had two flares total. My urologist noticed the difference before I even said anything.

Chelsey, 31★★★★★
Calms Inflammation Clinically Tested

"I drove two hours without stopping"

Hadn't been able to drive more than 30 minutes without pulling over in over a year. Around week six something shifted. Took a road trip last weekend and made it the whole way. I cried in the car.

Thymoquinone and interstitial cystitis - how it calms bladder inflammation and supports lining repair
How Does It Work for Bladder Pain?

Your bladder has a protective lining that keeps irritants out. When chronic inflammation breaks that lining down, everything that touches the bladder wall triggers pain, urgency, and frequency — no matter how carefully you eat.

Thymoquinone, the active compound in black seed oil, is studied for its effect on that inflammatory process — so the lining can actually start to rebuild.

Targets the inflammation — not just the symptoms
Backed by peer-reviewed research on TQ and bladder tissue
Works alongside your current meds and supplements
Cold-Pressed Black Seed Oil
Support Your Bladder at the Source
Loomi delivers thymoquinone standardized to 2% potency. Peer-reviewed research shows TQ is studied for its effect on the NF-κB inflammatory pathway — the upstream driver of bladder lining breakdown, mast cell activation, and the pain-urgency cycle that defines interstitial cystitis.*
Healthy
Inflammation
Bladder
Lining
Urgency &
Frequency
Flare
Recovery
Loomi Black Seed Oil for Bladder Support
82+
Clinical studies on black seed oil
2,000+
Years of traditional use
2%
Thymoquinone standardized potency
50K+
Orders shipped
Clinically Studied.
Standardized Potency.
Real Results.*
The only cold-pressed black seed oil standardized to 2% thymoquinone, backed by published research on inflammation and bladder tissue health.*
Try risk-free today
90-day money back guarantee

Common Questions

Frequently Asked Questions

Everything IC patients want to know before trying high-TQ black cumin seed oil.

Will this interfere with my Elmiron or hydroxyzine?

No. Thymoquinone works on the NF-κB inflammatory cascade. Elmiron works on the bladder lining surface. Hydroxyzine works on mast cell activation. They target different parts of the same system. Safe to take alongside both, as well as amitriptyline and D-mannose.

How long before I notice a difference?

Most women notice improved sleep and reduced nighttime urgency within 2-3 weeks. Flare frequency and daytime urgency typically start improving around weeks 5-7. We recommend committing to at least 8-12 weeks for the best picture of what it can do.

Can I take this alongside my IC diet?

Yes — and they complement each other. The IC diet reduces external triggers hitting your bladder lining. Thymoquinone is studied for its effect on the inflammation that degrades that lining from underneath. One removes the irritant. The other supports the environment so the lining can rebuild. Many of our customers follow both and report better results than either alone.

I've tried every supplement. Why would this be different?

Most IC supplements — D-mannose, marshmallow root, aloe vera — work on surface-level soothing or bacterial adhesion. None of them address the chronic inflammatory process that breaks down your bladder lining in the first place. Thymoquinone is studied for its effect on that upstream driver. It's a different mechanism entirely.

Where is your black seed oil sourced from?

Our Nigella sativa is sourced from the regions where it has been traditionally cultivated for centuries — primarily Egypt and Turkey, where the soil and climate produce the highest natural thymoquinone concentrations. The oil is cold-pressed at the source to preserve the active compound, then formulated, encapsulated, and third-party tested in the USA. Every batch is verified to meet our 2% TQ standardization before it ships.

How is this different from the black seed oil at my grocery store?

Most generic black seed oil contains less than 1% thymoquinone — the active compound behind the research results. Ours is standardized to 2% TQ, verified by third-party testing. The concentration matters. It's the difference between drinking grape juice and taking the active compound.

What is your return policy?

90-day money-back guarantee. Bladder lining repair takes time — we give you 90 days so you can take it consistently and see how your body responds. If you're not satisfied, contact us for a full refund. No questions asked.

Black Cumin Seed Oil

The Compound Studied for Its Effect on the Pathway Your Bladder Meds Can't Touch

Nigella sativa has been used for thousands of years across the Middle East, North Africa, and South Asia for inflammatory and urinary conditions. But tradition alone isn't why we're here.

Peer-reviewed research shows that thymoquinone — the active compound in black seed oil — is studied for its effect on the NF-κB inflammatory pathway. That's the same pathway implicated in GAG layer degradation, mast cell activation, and the chronic pain-urgency cycle that defines interstitial cystitis. Your current medications manage symptoms downstream. Nothing else in your stack addresses the inflammatory environment upstream.

"Thymoquinone has demonstrated significant anti-inflammatory, mast cell stabilizing, and tissue-protective properties across multiple peer-reviewed studies, with particular relevance to bladder and urinary tissue models."
— Published literature on Nigella sativa and TQ

Limited Stock Available

Your Treatment Plan Has Been Missing This

Cold-pressed Nigella sativa, standardized to 2% thymoquinone, third-party tested for purity and potency. The one compound studied for its effect on the inflammatory cascade your bladder medication can't touch. Delivered to your door with a 90-day money-back guarantee.

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90-Day Money-Back Guarantee — No Questions Asked
Rated 4.9 / 5  |  Trusted by 50,000+
They Felt the Shift. You Will Too.
5.0
"I slept through the night for the first time in months."
Was getting up four or five times a night. Around week three it dropped to twice. By week seven most nights I sleep straight through. That alone changed everything about my days.
Tamara J.
Nighttime UrgencyBetter Sleep
5.0
"My flares finally started spacing out."
Still on hydroxyzine and the IC diet. Added this about ten weeks ago. Used to flare every single week. Last month I had two flares total. My urologist noticed the difference before I even said anything.
Angela W.
Flare ReductionStacks Well
5.0
"Not even the same product as cheap Amazon BSO."
Bought cheap black seed oil on Amazon last year after reading about it in an IC group. Did nothing. This one is cold-pressed and standardized which apparently matters a lot. Felt the difference by week three. Not even the same product.
Sarah K.
Quality MattersReal Results
5.0
"I drove two hours without stopping."
Hadn't been able to drive more than 30 minutes without pulling over in over a year. Around week six something shifted. Took a road trip last weekend and made it the whole way. I cried in the car.
Chelsey N.
Urgency ReliefLife Changing
5.0
"Easiest supplement I've ever taken."
One capsule a day. No weird taste, no stomach issues, no complicated timing. My 3am bathroom trips stopped within two weeks and the burning has been noticeably calmer since month two. Easiest supplement I've ever taken.
Morgan C.
Easy To TakeReduced Burning
5.0
"My urologist asked what changed."
Showed my urologist my symptom diary after six weeks on Loomi. She asked what changed. Frequency down from 18 to 11 times a day. She told me to keep going.
Hannah B.
Frequency ReducedDoctor Noticed
5.0
"I can actually eat a tomato again."
Fourth bottle. I slowly reintroduced tomatoes and citrus over the last few weeks. No flare. I haven't been able to eat either in two years. I'm not saying I'm cured but my bladder is calmer than it's been since diagnosis.
Taylor S.
Diet FlexibilityCalmer Bladder
5.0
"Loomi is $30 and it's the only thing that actually helped."
I was spending over $200 a month on an IC supplement stack. D-mannose, marshmallow root, aloe vera, quercetin. Loomi is $30 and it's the only one that actually moved the needle. I still take D-mannose but I dropped everything else.
Danielle K.
Simplified StackReal Results
5.0
"My husband noticed before I did."
My husband noticed before I did. He said I hadn't asked him to pull over in weeks and I stopped canceling plans. He's the one who reordered it.
Carla M.
Life QualityUrgency Relief
5.0
"The 90-day guarantee is why I tried it. Month four is why I stayed."
I almost didn't try this because I've wasted so much money on IC supplements. The 90-day guarantee is why I did. I'm on month four and haven't thought about returning it once.
Rachel W.
Worth The TryLong-Term Results
3.0
"It works but it takes a while."
I didn't notice anything until about week six which felt like forever when you're in pain every day. Month three is when the urgency actually started easing. Just be patient with it.
Amanda R.
Takes TimeUrgency Relief
3.0
"I wish they had a bigger bottle option."
The capsules are fine but I wish they had a bigger bottle option. 60 capsules is only a one month supply and I'd rather just buy three months at once instead of reordering every few weeks.
Michelle P.
Bottle SizeReorder Frequency
3.0
"I almost gave up at week three."
Took about five weeks before I felt any difference at all. I almost gave up at week three. My nighttime trips improved first then eventually the daytime urgency started calming. It's working but the wait was frustrating.
Katie L.
Patience RequiredUrgency & Sleep
3.0
"The only thing that actually moved the needle."
I like the product but the bottle is small for the price. My marshmallow root gives me a three month supply for around the same cost. That said this is the only thing that actually reduced my flare frequency so I keep buying it.
Jasmine H.
Value ConcernFlare Reduction
3.0
"Helped my urgency but not my pain."
Helped my urgency and my sleep but didn't do as much for the pelvic pain which was honestly my main reason for trying it. Still taking it because the frequency improvement is real but I was hoping for more on the pain side.
Stephanie M.
Urgency ReliefMixed Results